Microfluidics and Lab-on-a-Chip

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††††††††† DongqingLi,Ph.D., Professor

††††††††† Department of Mechanical & Mechatronics Engineering

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Tel 519-888-4567 Ext 38682

Email: dongqing@mme.uwaterloo.ca

 

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Click here to see some pictures of Dr. Li's Microfluidics Lab

Research Interests

Microfluidics and Nanofluidics: Fundamental understanding of liquid flow and mass (molecules, particles and cells) transfer in microchannels and nanochannels is critical to the design and process control of various Lab-on-a-Chip, or Microfluidic devices used in biomedical diagnostics and analysis. Many transport processes in micro- and nano-channels are dominated by the complicated electrokinetic phenomena at the micron scale. Dr.Li's group develops theoretical models and conducts numerical simulations for various electrokinetic phenomena and transport processes in micro-/nano-channels for on-chip microfluidic applications. Experimental studies are also carried out to investigate the characteristics of various electrokinetic microfluidic processes. The liquid flow and mass transfer are generated by applied electrical fields. Liquid flow and mass transfer (ions, particles and cells) in microchannels are visualized and measured by fluorescent visualization and m-PIV techniques. Microchannels and lab-on-a-chip devices are made by a soft-photolithography and 3D printing rapid prototyping facility in Dr. Li's lab.

Lab-on-a-Chip Devices: Using the knowledge developed from the fundamental research in microfluidic and nanofluidic phenomena, Dr. Li's lab. has developed various on-chip microfluidic devices such as Immunoassay Lab-on-a-chip for bacterial and virus detection, Real-Time PCR detection chips, DNA-RNA detection lab-on-a-chip for bacterial and virus detection, Neuraminidase enzymatic assay lab-on-a-chip for virus detection.The developed handheld lab-on-chip devices and technology provide powerful tools, at greatly reduced cost, for applications in biomedical diagnosis, environmental monitoring, food safety, forensics and anti-bioterrorism.

Selected Publications

252 journal papers and 2 books are listed here.

Click here to see members of Dr. Liís group.

Courses taught by Dr. Li:

 

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